Type: Process Essays
Sample donated: Stacey Miller
Last updated: October 2, 2019
Axel, Richard. and Buck, Linda B.
“Odorant Receptors and the Organization of the Olfactory System.” The Laureates. October 2004.Odorant Receptors and the Organization of the Olfactory SystemOne of our five senses and is possibly one of the most mysterious is our sense of smell.
In simple words it is astonishing and up until recently not understandable just how many different smells we are able to recognize and remember. It is thanks to Axel and Buck who were able to answer this query on how this works. The both of them discovered a huge family of genes that have many receptors as well. These receptors are on olfactory receptor cells, that are on the top of nasal epithelium, detect the inhaled odorant molecules.Every olfactory receptor cell has one kind of odorant receptor. Every one of these receptors can detect a number of ordants.
The olfactory receptor cells that we have, are designed to work at their fullest for just a few ordants however. This is because cells send processes to different micro domains called glomeruli which is the main area in the brain for olfactory. There the information is combined to make patterns. Thus allowing for consciously experiencing smells and recall that olfactory memory in later occasions.
As one can tell, the olfactory system is extremely important for the quality of one’s life to increase substantially.It is due to our sense of smell that is responsible for things tasting yummy as it assists in aiding the things we see as good. A unique and specific smell can be the one thing that acts as a trigger to different memories from as far back as our childhoods or very deep and sentimental memories that could be good or bad. Losing the ability to smell could be a very severe problem regarding the quality of life as it would be extremely deteriorated and we would not to be able to see and experience food and hazards such as smoke and chemicals.All things alive can tell apart and sense the changes and differences in their environment. To ID food necessary for life and to avoid the very disgusting putrid/rotten foods the sense of smell is very important. The sense of smell is not only just needed but also essential for the continuation of many newborns.
Without this sense of smell newborn pups would not be able to find the mammary glands of their mothers, without it they will obviously die. The sense of smell or olfaction is indeed greatly needed as adults as well, this is because they see and perceive the world largely by their sense of smell.The sense of smell is the first of our five senses to be develo broken down by using the modern molecular techniques that scientist have developed. When a smell receptor is activated by a smell a signal notifies the smell receptor cell and it goes to the brain through a nerve process. Each smell receptor activates something that is called a G protein that is coupled, the protein then equalizes the formation of cAMP. This messenger then activate ion channel that open and is activated.A type a smell receptor in each olfactory receptor so showed that each single olfactory receptor so has only one of the smell receptor genes. This meant that there are several types of olfactory receptor cells just like smell receptors.
A majority of snails or made several smell molecules and each one of these smell molecules activates many smell receptors. This then leads to a combinational cold making hey smell pattern. This is the sole base of one’s mobility of recognizing and memorizing more than 10,000 different smells.The basic key points that Axel and Buck laid out for this system seems to also adhere to the other of the 5 senses. Pheromones can cause different actions. They saw that they are identified by two other families centered at the nasal epithelium.The tongue with its taste buds have a whole other family GPCR there the witch is conjoined with the sense of taste.