The social services sent an appointment letters out addressed to Mrs Patel written in her own language, even though Mrs Patel does not understand English she must still be treated as an equal. Mrs Patel or a family member was to phone the number at the bottom of the letter to contact a member of staff who spoke different languages. The appointment was confirmed on an appropriate date and time,

Thensomeone else may argue “if thegenes of the next generation could be chosen, we would have many more intelligent,rational, and logical children”.However, “revolution works at the margins, and it does so throughtrade-offs”. (KOZUBEK, 2017) For example, the infamous “APOE4 variant, thesingle strongest risk variant for late-onset Alzheimer’s disease, remains at15% frequency in the population—one reason is that it may also up Vitamin D.”(KOZUBEK, 2017) Overall, engineeredtraits may advance the mankind in a temporary period,

IL33 is an immune molecule which was found toreverse the symptoms and cognitive decline of  Alzheimer’s disease’s in mice in studypublished in the journal “proceedings of the national academy of Sciences(PNAS)”.A mouse model of Alzheimer’s disease called APP/PS1 was used to check theeffect of this injection. These mice displayed cognitive decline as well as theaccumulation of beta amyloid proteins in their brains both of which are symptomsof the disease. Studies

Though some genes are involved in ADpathogenesis, genetically inherited Alzheimer’s disease accounts only 10-12 percentof AD case (Blennow,de Leon et al. 2006).Onset of genetically identified forms of Alzheimer disease usually incident inearly life of individuals (Blennow,de Leon et al. 2006).The current idea is that there are atleast two types of AD- sporadic/late onsetand familial/early onset cases of Alzheimer disease.i.                    FamilialAlzheimer’s disease (FAD)WhenAlzheimer disease is caused by inherited mutations in some

Approximatly 38,000 people in Ireland are affectedby Alzheimer’s, a figure which is growing every day. Because this disease is soprominent in our society it is important for us, as chemists, to not only beaware of the facts and statistics, but also what chemical reaction andimbalances make this disease as devastating and fast acting as it is. In peoplediagnosed with dementia and Alzheimer’s, there is shrinking of the CerebralCortex which is

1.     Introduction1.1.   Alzheimer’s DiseaseAlzheimer’sdisease is a brain disorder that progresses over time.  It most commonly happens in patients’ latestage life (Burns& Iliffe, 2009). It involves the death of nerve cells and thus leads to the reduction ofbrain volume (Fig. 1), which impactbrain functions.  The most noticeable early stage symptomincludes short-term memory loss.  As thedisease progress, patients may show disturbances in language, orientation,reasoning and perception (Weiner et al.,2010).   At the same time,both

The global prevalence ofAlzheimer’s Disease (AD) has increased significantly and has a huge economicimpact. It most common form of dementia, is now representing one of the largestglobal healthcare challenges and estimated that approximate 25 million peopleworldwide suffer from this dreadful condition (Mayeux and Sano, 1999).Although, the etiology of Alzheimer’s disease and its pathophysiology is stillunclear. Accumulation of amyloid-beta (A?) in the brain is hypothesized totrigger pathogenic cascades that eventually lead

Main causal contrast of the theory The frequency of Alzheimer’s disease in persons exposed to high sugar consumption is greater than frequency of Alzheimer’ disease in persons exposed to high sugar consumption if they had not been exposed. b. Hypotheses in operationalized form HYPOTHESIS 1: High sugar intake (E) causes Alzheimer’s disease (D) beyond chance. (Main Effect and its magnitude) HYPOTHESIS 2: Chronic stress is an alternative explanation for the